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抗原反应的解释

2020-01-06 20:26
所谓抗原的反应原性是指能与由它刺激所产生的抗体或致敏淋巴细胞发生特异性反应。具备免疫原性和反应原性两种能力的物质称为完全抗原,如病原体、异种动物血清等。只具有反应原性而没有免
抗原的反应
抗原的反应疫原性的物质,称为半抗原,如青霉素、磺胺等。半抗原没有免疫原性,不会引起免疫反应。但在某些特殊情况下,如果半抗原和大分子蛋白质结合以后,就获得了免疫原性而变成完全抗原,也就可以刺激免疫系统产生抗体和效应细胞。在青霉素进入体内后,如果其降解产物和组织蛋白结合,就获得了免疫原性,并刺激免疫系统产生抗青霉素抗体。当青霉素再次注射人体内时,抗青霉素抗体立即与青霉素结合,产生病理性免疫反应,出现皮疹或过敏性休克,甚至危及生命。

Antigenic reactivity is defined as the ability to react specifically to an antibody or lymphocyte produced by its stimulation. The immunogenicity and reactivity of two kinds of ability of the material known as complete antigen, such as pathogens, xenogeneic animal serum. A reactive immunogenic substance, called a Hapten, such as penicillin or sulfanilamide, that is reactive in nature but not immune to the antigen. Haptens have no immunogenicity and do not cause an immune response. However, in some special cases, if the hapten and the macromolecule protein after binding, they have acquired immunogenicity and become a complete antigen, which can stimulate the immune system to produce antibodies and effector cells. When penicillin enters the body, if its degradation products bind to tissue proteins, it acquires immunogenicity and stimulates the immune system to produce anti-penicillin antibodies. When Penicillin is re-injected into the body, anti-penicillin antibodies immediately bind to penicillin, producing a pathological immune response, a rash or Anaphylaxis, or even life-threatening
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